What is going on with this Klebsiella?


Carbapenem_E-test

This is a not so infrequent meropenem E-test of a carbapenemase-producing K. pneumoniae (OXA-48). There is a well-defined halo around the stripe but as it can be easily seen, there are colonies within the halo.

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  • What do these inside-the-halo colonies mean?
  • Are these colonies resistant to meropenem?
  • Mutant, heteroresistant strains or simply an artifact?
  • How  should MIC be read?

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Comments are welcome!!!!

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